How Bacteria can be Genetically Engineered to Produce a Human Protein?

How bacteria can be genetically engineered to produce a human protein?

HOW BACTERIA CAN BE GENETICALLY ENGINEERED TO PRODUCE A HUMAN PROTEIN:

OVERVIEW:

Bacteria is genetically modified to produce useful human proteins such as human growth hormone and human insulin.

Genetic engineering can be used to create organisms that produce large amounts of useful substances – for example, bacteria can be engineered to produce human insulin to treat diabetics.

Genetic engineering involves altering the genetic code of an organism by inserting a gene or genes from another organism.

EXAMPLE:

HUman growth hormone and human insulin.

WHY BACTERIA IS USED ?

Bacteria can be genetically engineered (genetically modified) to produce useful human proteins including human growth hormone and human insulin.

One advantage of using bacteria is that they can be grown in large fermenters, producing large amounts of these useful proteins.

STEPS OF HOW BACTERIA CAN BE GENETICALLY ENGINEERED TO PRODUCE A HUMAN PROTEIN:

Desired gene is identified

The gene is removed from the organisms DNA

The DNA in other organism or bacterial DNA is cut open

The gene is inserted into the cut DNA

The inserted gene works in the transgenic (genetically engineered) organism or bacteria.

The transgenic organism or bacterium is cloned to make lots of identical copies….

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