What kinds of chromosomal rearrangements can lead to gene dose deleterious effects in 3) individuals that carry them? A) duplications B) deletions C) inversions D) reciprocal translocations E) A and B are correct

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    Answer is : E) A and B are correct Gene dosage is defined as number of times a given gene is present in the nucleus of cell. Imbalance in gene dosage alter the amount of a particular protein relative to all other proteins, and lead to variety of phenotypic effects. Deletion causes loss of part of a chromosome that results on monosomy for that segment of the chromosome. Duplication results in doubling of part of a chromosome, resulting in trisomy for that segment. Thus, gene dosage result is either decrease or increase in that part of a chromosome...

    • 06 Dec 2017 @ 08:32

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